![]() ![]() This cycle is repeated, causing fever each time parasites break free and invade blood cells. In the bloodstream, the merozoites invade red blood cells ( erythrocytes) and multiply again until the cells burst.The vesicles eventually disintegrate, freeing the merozoites to enter the blood phase of their development.* In an animal model, the parasites, in the form of merozoites, are released from the liver cells in vesicles, journey through the heart, and arrive in the lungs, where they settle within lung capillaries.The sporozoites multiply asexually in the liver cells over the next 7 to 10 days, causing no symptoms.The sporozoites pass quickly into the human liver.Malaria infection begins when an infected female Anopheles mosquito bites a person, injecting Plasmodium parasites, in the form of sporozoites, into the bloodstream.In addition, the parasite has developed a series of strategies that allow it to confuse, hide, and misdirect the human immune system. Understanding which of these can be a useful target for vaccine development has been complicated. ![]() ![]() The parasite also changes through several life stages even while in the human host, presenting different antigens at different stages of its life cycle. The size and genetic complexity of the parasite mean that each infection presents thousands of antigens (proteins) to the human immune system. The malaria parasite develops both in humans and in the female Anopheles mosquitoes. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |